Studies on Carcinoembryonic Antigen in Various Liver Diseases
نویسندگان
چکیده
منابع مشابه
Carcinoembryonic antigen in serum in diseases of the liver and pancreas.
Carcinoembryonic antigen (CEA) was measured in whole serum and in serum extracted with perchloric acid by microradioimmunoassay in patients with benign and malignant diseases of the liver and pancreas. The level of detectability was 5 ng per ml. This level or greater was present in the serum of 50% of patients with chronic diffuse liver disease, 64% with pancreatitis, 94% with cancer of the dig...
متن کاملPhysical characterization and structural studies of the carcinoembryonic antigen.
Knowledge of the structure of carcinoembryonic antigen (CEA) is essential if we are to understand the relationship of this molecule to similar, possibly cross-reacting, molecules present in nonmalignant states. Electron microscopy shows that at neutral pH, CEA particles consist of homogeneous, morphologically distinctive, twisted rod-shaped particles, about 9 X 40 nm. The carbohydrate structure...
متن کاملMutations in the carcinoembryonic antigen gene in colorectal cancer patients: implications on liver metastasis.
Carcinoembryonic antigen (CEA) expression is used clinically to monitor patients with colorectal and other cancers. A subset of patients have extraordinarily high CEA levels that cannot be attributed solely to tumor load. We have shown mutations in the region of CEA (PELPK motif) responsible for its hepatic clearance in three of eight patients with high CEA levels. We used denaturing high-perfo...
متن کاملSerum Levels of Carcinoembryonic Antigen and a Tumor-extracted Carcinoembryonic Antigen-related Antigen in Cancer Patients1
Levels of Carcinoembryonic antigen (CEA) and a tumor-ex tracted CEA-related antigen (TEX) were determined in sera from patients with carcinomas of the breast, colon, lung, head and neck, and a number of miscellaneous categories. The purpose of this study was to compare the levels of each antigen at various stages of malignant disease. Competitive radioimmunoassays developed in our laboratory we...
متن کاملSerum levels of carcinoembryonic antigen and a tumor-extracted carcinoembryonic antigen-related antigen in cancer patients.
Levels of carcinoembryonic antigen (CEA) and a tumor-extracted CEA-related antigen (TEX) were determined in sera from patients with carcinomas of the breast, colon, lung, head and neck, and a number of miscellaneous categories. The purpose of this study was to compare the levels of each antigen at various stages of malignant disease. Competitive radioimmunoassays developed in our laboratory wer...
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ژورنال
عنوان ژورنال: Kanzo
سال: 1978
ISSN: 0451-4203,1881-3593
DOI: 10.2957/kanzo.19.942